In this day and age when every day there seems to be some new "Miracle Cure," Lotion or Potion it is only to be expected that you would react with some level of skepticism.

With this in mind we have tried to compile articles, books, websites and research papers to help you further your reading and understanding of Ashitaba and its beneficial effects on your health.

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"The U.S. has the most drug use of any country, yet in terms of longevity, the people in 17 countries in Europe and Asia live longer.
Prescription drug use in Europe averages about 46% less than in the U.S. In Japan, it is almost 80% less; and in China, nearly 95% less. However, the use of natural medicines is proportionally higher in Europe and Asia, with the Japanese and Chinese nearing total devotion to medicines derived from plants."
         Source: Gero Vital International

It is also interesting to note: "In rural China, doctors are paid only when you are well. If you get sick, you don't pay them. As you can see, they have a vested interest in keeping you healthy. That is probably the reason the Chinese live longer and are healthier. Too bad we don't have that system here." - Ibid.

"The doctor of the future will give no medicine, but will interest his patients in the care of the human frame, in diet and in the cause & prevention of disease."
         - Thomas Edison -

www.ashitaba.com

Ashitaba, A Medicinal Plant and Health Method By Kazuo Hida

Research on the Effects of Ashitaba, Angelica Keiskei Koidzumi By Dr. Kevin Lance Jones, L.Ac., O.M.D.

Tooru Okuyama, Miraculous Ashitaba, Heart shuppan, 1994

Kimie Baba, Healthy vegetable Ashitaba, Chikuma shuubansha, 1995

Hida, Medicinal herb Ashitaba, Tsuchiya shyoten, 1991

Kazuo Izawa, Color Encyclopedia of Medicinal Herbs, Shufunotomo-sha, p501, 1998

TAKARA's scientists discover compounds enhancing in vivo production of Nerve Growth Factor

What's Ashitaba?

What is Ashitaba?

BOOK TITLE : "Miracles by Ashitaba" by Dr. S. Yamanouchi PUBLISHER : Heart Publishing
ISBN :4-89295-037-8 C2077 P800E


BOOK TITLE : "Ashitaba, the Nutritional Treasure House" by Dr. S. Yamanouchi
PUBLISHER : Heart Publishing ISBN :4-8069-0262-4 C2047-P1000E


BOOK TITLE:"Marvelous Ashitaba" by Dr. H. Goto
PUBLISHER : Heart Publishing ISBN : 4-938564-52-1 C0277 P750E

Research Study Report by Dr. Kimie Baba

Chalcones and Flavonoids

Xanthohumol Research Xanthohumol, is a prenylated chalcone, found in hops. One would have to drink 120 gallons of beer per day to have any significant biological effect.

Unique Composition of Ashitaba Chalcone

CHALCONE (Xanthoangelol) in Hachi Jo Island Ashitaba inhibits stress-affected ulcer.

CHALCONE has Antibacterial Effect

How CHALCONE prevents Thrombus

The Interaction of Chalcones with Tubulin, N. J. Lawrence, A. T. McGown, S. Ducki and J. A. Hadfield, Anticancer Drug Design, 2000, 15, 135.

Potent antimitotic and cell growth inhibitory properties of substituted chalcones, S. Ducki, R. Forrest, J. A. Hadfield, A. Kendall, N. J. Lawrence, A. T. McGown and D. Rennison, Biorg. Med. Chem. Lett., 1998, 8, 1051.

Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro. J Agric Food Chem. 2000 Sep;48(9):3876-84.

Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells. Cancer Lett. 2000 Feb 28;149(1-2):21-9.

Inhibition of gastric H+, K(+)-ATPase by chalcone derivatives, xanthoangelol and 4-hydroxyderricin, from Angelica keiskei Koidzumi.Murakami S, Kijima H, Isobe Y, Muramatsu M, Aihara H, Otomo S, Baba K, Kozawa M.

Medical Attributes of Humulus lupulus - Hops This research is about the chalcones in Hops which was identified before the Chalcones in Ashitaba

Xanthohumols, diacylglycerol acyltransferase inhibitors, from Humulus lupulus.Tabata N, Ito M, Tomoda H, Omura S.

Food Fiber and Health

Green Foods: A Research Perspective by David Sandoval Nutraceuticals World May 2003

Effects of angiotensin I-converting enzyme inhibitor from Ashitaba (Angelica keiskei) on blood pressure of spontaneously hypertensive rats.Shimizu E, Hayashi A, Takahashi R, Aoyagi Y, Murakami T, Kimoto K.

www.cancersalves.com/ article on Blood Purification

Anticancer Drug Design

Experiments suggest hop compounds fight cancer

Ashitaba Helps to Inhibit Cancer
Linked Parallel Synthesis and MTT Bioassay Screening of Substituted Chalcones, N. J. Lawrence, D. Rennison, A. T. McGown, S. Ducki, L. A. Gul, J. A. Hadfield and N. Khan, J. Comb. Chem., 2001, 3, in press.

The Interaction of Chalcones with Tubulin, N. J. Lawrence, A. T. McGown, S. Ducki and J. A. Hadfield, Anticancer Drug Design, 2000, 15, 135.

Potent antimitotic and cell growth inhibitory properties of substituted chalcones, S. Ducki, R. Forrest, J. A. Hadfield, A. Kendall, N. J. Lawrence, A. T. McGown and D. Rennison, Biorg. Med. Chem. Lett., 1998, 8, 1051.

Prenylated chalcones and flavanones as inducers of quinone reductase in mouse Hepa 1c1c7 cells. Cancer Lett. 2000 Feb 28;149(1-2):21-9.

Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice. Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J.

In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts.Hashimoto K, Kawamata S, Usui N, Tanaka A, Uda Y.

Ashitaba and AIDS

"Dong Quai" or "Angelica sinensis".

American Herbal Pharmacopoeia Publishes Dang Gui Root (Angelica sinensis) Monograph

Study Ties Hormone Therapy to Bolder, Stealthier Cancer by Thomas H.Maugh II Times staff writer 6/25/2003

Menopause? PMS?

Relationship Between Long Durations and Different Regimens of Hormone Therapy and... Li et al. JAMA.2003; 289: 3254-3263.

Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus

Treating hot flushes without hormone replacement therapy. J Fam Pract. 2003 Apr;52(4):291-6. Review. No abstract available. PMID: 1268109
Use of alternative and complementary medicine in menopause. Int J Gynaecol Obstet. 2002 Dec;79(3):195-207. Review. PMID: 12445983Kang HJ, Ansbacher R, Hammoud MM.

http://www.naturalhealthnotebook.com/ on Blood Purification

www.cancersalves.com/ article on Blood Purification

Colon Cleansing by Shirley Trickett & Karen Brody

Irritable Bowel Syndrome & Diverticulosis (Thorsons, revised 1999)

Detoxification - An Ayurvedic Perspective New Again! by Anna Selby (Ulysses Press, 1999) offers a 28-day detoxification plan General Detoxification and Cleansing© Elson M. Haas M.D.

Detoxification -The Growing Problem Of Toxicity

Introduction to Internal Body Cleansing and Detoxification

Food Fiber and Health

Anti-Oxidants for Disease Prevention by Chuck Balzer, MS RD

Antioxidant Flavinoids: Structure, Function and Clinical Usage By Alan L. Miller, ND

Antioxidant Activities of Flavonoids

Antioxidant Activity in Chinese Foods

The Antioxidants by Ron Kennedy, M.D., Santa Rosa, California

Learn how you could help your body with antioxidants !!

All About Antioxidants

Antioxidant Capacity and Health Benefits of Fruits and Vegetables

Antioxidants

Oxygen Radical Absorption Capacity (ORAC) Assay For Measuring Antioxidant Activity

Anti Aging Directory - Antioxidant Links

The Color of Health - Why Nutrients Called Flavonoids Are Good For You by Jack Challem, The Nutrition ReporterT

Chalcones and Flavonoids

Flavonoids in Tea

Antioxidant Flavonoids(listed in order of decreasing potency)

Antioxidant Activities of Flavonoids

USDA Database for the Flavonoid Content of Selected Foods

Finessing the Flavonoids

A Critical Look at the Flavonoids and Some Sound Recommendationsby Jack Challem

"There is evidence that free-radical oxidation of LDL plays an important part in atherogenesis," Hertog and Feskins wrote in Lancet (Oct. 23,1993;342:1007-11). "Flavonoids are scavengers of free radicals...It is possible that quercetin and other flavonoids reduce the rate of formation of oxidised LDL and thus inhibit the growth of atherosclerotic plaques."

Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes ;Food Chem Toxicol. 2001 May;39(5):437-45.

Prenylflavonoids have anti-allergic, anti-inflammatory, anti-viral, anti-fungal, anti-bacterial, anti-oxidizing properties.
C.L.. Miranda et al: In Food and chemical Toxicology 37 (1999) 273 - 285; J.F. Stevens et al:In J Am. Soc. Brew. Chem. 56(4) 136 - 145, 1998 ; A Alt et al: Deutsches Krebsforschungszentrum. Abt. C0202, D-69129 Heidelberg.

Phytochemicals

Phenolic compound

Phytochemicals: Nutrients Of The Future By Marcia Zimmerman C.N.

The benefits of tea flavonoids were confirmed earlier this year by researchers at the Saitama Cancer Research Center, Japan. K. Imai, PhD, and K. Nakachi, PhD, studied 1,371 men enrolled in a 40-year study of eating habits and health. They reported that elderly men who drank 10 or more cups of green tea daily had lower blood levels of cholesterol and triglycerides than men who drank less of the tea. "Consumption of green tea was significantly associated with lower serum concentrations of lipids and lipoproteins," they wrote in the British Medical Journal (March 18, 1995;310:693-6). "An increase in consumption substantially decreased serum total cholesterol and triglyceride concentrations, and this strong association remained almost unaltered even after age, cigarette smoking, alcohol consumption, and relative body weight were controlled for." The heavy tea drinkers also benefited from higher blood levels of the HDL and lower levels of the "bad" low-density lipoprotein (LDL) form of cholesterol. In addition, they had lower levels of certain liver enzymes, suggesting a reduced risk of liver disease. Drinking either green or black tea also protects against skin cancer by ultraviolet (UV) light and hazardous chemicals. In an experiment, Allan Conney, Ph.D., of the College of Pharmacy, Rutgers University, brewed four types of teas in concentrations comparable to what people drink: black tea, green tea, decaffeinated black tea, and decaffeinated green tea. He gave one type of each tea to four different groups of mice as their sole source of drinking fluid, then exposed them to either cancer-causing UV radiation or chemicals. For comparison's sake, he gave another group of mice plain water to drink. Conney reported in Cancer Research (July 1, 1994;54:3428-35) that the teas "markedly inhibited" the numbers and sizes of tumors.

Organic Food Promotes Health & Ethical Choice

angelica

Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus

Treating hot flushes without hormone replacement therapy. J Fam Pract. 2003 Apr;52(4):291-6. Review. No abstract available. PMID: 1268109
Use of alternative and complementary medicine in menopause. Int J Gynaecol Obstet. 2002 Dec;79(3):195-207. Review. PMID: 12445983Kang HJ, Ansbacher R, Hammoud MM.

"Dong Quai" or "Angelica sinensis".

American Herbal Pharmacopoeia Publishes Dang Gui Root (Angelica sinensis) Monograph



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